Ingredient Intelligence
Regulatory status, enforcement history, and business impact analysis for FDA-monitored ingredients — updated as new actions are published.
Parabens: FDA Status, State Bans & Global Restrictions for Food and Cosmetics
Parabens face a rapidly shifting regulatory landscape — from California's food and cosmetics bans to EU concentration limits and 20+ state-level restrictions. Here's what food and cosmetics companies need to know.
Read more →NMN (Nicotinamide Mononucleotide): FDA Drug Preclusion Reversal & Supplement Status
After a three-year regulatory battle, the FDA reversed its drug preclusion determination for NMN in September 2025, confirming it is lawful in dietary supplements. Here is everything regulatory professionals need to know.
Read more →Lead in Food, Supplements, and Cosmetics: FDA Regulatory Intelligence
Lead is a toxic heavy metal that contaminates food, dietary supplements, and cosmetics through environmental exposure, processing equipment, and occasionally deliberate adulteration. FDA's Closer to Zero initiative is setting action levels for baby food, juice, and candy, while the 2023 WanaBana applesauce recall exposed systemic failures in spice supply chain oversight.
Read more →Kratom (Mitragyna speciosa): FDA Regulatory Status, State Bans & 7-OH Scheduling
Kratom remains unapproved by the FDA for any use, subject to Import Alert 54-15, and caught in a regulatory tug-of-war between state bans, Consumer Protection Acts, and a federal push to schedule concentrated 7-hydroxymitragynine. Here is what companies in the dietary supplement and functional beverage space need to track.
Read more →Talc: FDA Review, IARC Reclassification & Regulatory Intelligence
Comprehensive regulatory intelligence on talc (magnesium silicate), covering FDA expert panel recommendations, IARC Group 2A reclassification, EU Category 1B carcinogen classification, the J&J litigation, asbestos contamination testing, MoCRA implications, and state-level bans on talc in menstrual products.
Read more →Formaldehyde: FDA Regulatory Status, State Bans & Global Restrictions
Formaldehyde is an IARC Group 1 carcinogen facing an accelerating patchwork of state bans in cosmetics, a repeatedly delayed federal proposed rule, active mass tort litigation with 11,400+ pending cases, and an August 2026 EU REACH deadline. Here is what FDA-regulated companies need to know.
Read more →CBD (Cannabidiol): FDA Regulation, Warning Letters & Compliance Guide
CBD remains illegal in food and dietary supplements under federal law despite widespread availability. Track FDA enforcement, Section 781 changes, and the legislative path forward.
Read more →Brominated Vegetable Oil (BVO): FDA Revocation, State Bans, and What It Means for Beverage Companies
BVO became the first food additive the FDA revoked in decades when it finalized 21 CFR 180.30 removal in July 2024. With the compliance deadline passed in August 2025 and California AB 418 enforcement looming in 2027, beverage manufacturers face a new enforcement reality.
Read more →Azodicarbonamide (ADA): FDA Status, International Bans & Regulatory Intelligence
Comprehensive regulatory intelligence on azodicarbonamide (ADA), the 'yoga mat chemical' — FDA-approved under 21 CFR 172.806 at 45 ppm but banned in the EU, UK, Australia, and Singapore. Now on FDA's post-market reassessment priority list under MAHA, with Texas school meal bans and warning label requirements taking effect in 2026-2027.
Read more →Propylparaben: California Ban, Endocrine Disruption Concerns & FDA Status
Propylparaben faces a California food ban effective Jan 2027, FDA post-market review in 2026, and West Virginia restrictions. Full regulatory intelligence for food and cosmetic companies.
Read more →Carrageenan: FDA GRAS Status, IARC Classification & Regulatory Intelligence
Comprehensive regulatory intelligence on carrageenan (E407), covering FDA GRAS status under 21 CFR 172.620, the critical distinction between food-grade carrageenan and degraded carrageenan (poligeenan), IARC classification, NOSB organic delisting controversy, and EFSA re-evaluation.
Read more →Sodium Nitrite: FDA Status, IARC Processed Meat Classification & Regulatory Intelligence
Comprehensive regulatory intelligence on sodium nitrite (E250), covering FDA prior-sanctioned status under 21 CFR 181.34, USDA-FSIS limits, IARC Group 1 processed meat classification, EU 2023/2108 lower limits effective October 2025, nitrosamine formation concerns, and the 'uncured' labeling controversy.
Read more →Sucralose: FDA Status, Emerging Safety Concerns & Regulatory Intelligence
Comprehensive regulatory intelligence on sucralose (Splenda/E955), covering FDA approval under 21 CFR 172.831, the 2026 EFSA re-evaluation, sucralose-6-acetate genotoxicity findings, MAHA Commission scrutiny, and state-level school food restrictions.
Read more →FD&C Green No. 3 (Fast Green FCF): FDA Phase-Out, State Bans & Compliance Guide
Green 3 is the least-used FDA-certified dye, now targeted for voluntary phase-out by end of 2026. State bans and reformulation guidance for affected manufacturers.
Read more →FD&C Blue No. 2 (Indigotine): FDA Phase-Out, State Bans & Compliance Guide
FD&C Blue No. 2 faces voluntary FDA phase-out by end of 2027, state-level school bans in 5 states, and growing reformulation pressure. What companies need to know now.
Read more →FD&C Blue No. 1 (Brilliant Blue): FDA Phase-Out, State Bans & Compliance Guide
Comprehensive regulatory intelligence on FD&C Blue No. 1 — FDA voluntary phase-out timeline, state-level school bans, EU status, natural alternatives, and compliance strategy.
Read more →Aspartame: IARC Cancer Classification, FDA Response & Regulatory Outlook
IARC classified aspartame as Group 2B 'possibly carcinogenic' in 2023, but FDA and JECFA reaffirmed safety. Track the evolving regulatory landscape for this high-intensity sweetener.
Read more →Potassium Bromate: FDA Status, State Bans & Global Regulatory Outlook
Potassium bromate remains permitted in US baked goods under 21 CFR 136 while banned in the EU, Canada, China, India, Brazil, and most major economies. California's AB 418 ban takes effect Jan 1, 2027. FDA review ongoing since March 2024.
Read more →Yellow No. 6 (Sunset Yellow): FDA Phase-Out, State Bans & Contaminant Concerns
FD&C Yellow No. 6 is targeted for voluntary phase-out by end of 2026. State school food bans already in effect. EU mandatory warning labels since 2010. Compliance guide for food and pharma companies.
Read more →Yellow No. 5 (Tartrazine): FDA Phase-Out, State Bans & Compliance Guide
FD&C Yellow No. 5 is targeted for voluntary phase-out by end of 2026 under the MAHA initiative. State bans already in effect. Complete compliance guide for food and pharma companies.
Read more →BHA (Butylated Hydroxyanisole): FDA Reassessment, Carcinogen Classification & State Bans
BHA is under formal FDA post-market reassessment as of February 2026. Listed as a carcinogen by NTP and IARC. Banned in West Virginia (injunction pending). Complete compliance guide.
Read more →Red 40 (Allura Red AC): FDA Phase-Out, State Bans & Reformulation Guide
FD&C Red No. 40 is the most widely used synthetic food dye in the US, targeted for voluntary phase-out by end of 2026. State bans already in effect. Complete compliance guide.
Read more →PFAS (Per- and Polyfluoroalkyl Substances) in Food & Cosmetics: Regulatory Intelligence
Comprehensive regulatory tracker for PFAS in food contact materials, food packaging, and cosmetics. Covers the FDA voluntary phase-out, 15+ state bans, MoCRA cosmetics report, EU REACH restriction proposal, and EPA drinking water limits.
Read more →Titanium Dioxide (TiO2): EU Ban, US Status & Global Compliance
Titanium dioxide is banned in EU food since August 2022 but remains an authorized color additive in the US under 21 CFR 73.575. FDA review is accelerating under MAHA pressure.
Read more →Red No. 3 (Erythrosine): FDA Ban, Deadlines & What Companies Must Do
FD&C Red No. 3 is banned in food (Jan 2027) and drugs (Jan 2028). Complete compliance guide: deadlines, state bans, reformulation steps, and enforcement outlook.
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